The key difference between HRT (hormone replacement therapy) and bioidentical hormones is in the source and molecular makeup of the hormones used.
HRT refers to administering FDA-approved synthetic hormones like estradiol, progesterone, or testosterone to treat symptoms of hormone deficiency. These molecules may have a slightly different structure than the hormones naturally produced in the human body.
- Commonly used HRT hormones:
- Premarin (conjugated estrogens from pregnant horse urine)
- Provera (medroxyprogesterone acetate)
- Estrace (estradiol)
- HRT hormones are standardized and approved by regulatory agencies.
- Widely studied in large clinical trials for safety and efficacy.
- Sold commercially by pharmaceutical companies.
In contrast,
bioidentical hormones are chemically identical molecules to those produced naturally in the human body like estradiol, progesterone, testosterone,
DHEA etc.
- Bioidentical hormones are custom compounded based on a patient's need. This allows personalized dosing.
- Made from plant sources like soy or yams.
- Bypasses FDA approval process indicating less safety data might be available.
When choosing between HRT and bioidenticals, consider these key factors:
Safety
HRT hormones have known safety profiles from decades of study. Risks depend on type of hormones used.
Comparatively lesser data on long term safety of bioidentical custom compounded hormones. But being identical molecules, they are hypothesized to be safer.
Efficacy
Both aim to relieve menopausal symptoms like
hot flashes, vaginal dryness etc. by replacing deficient hormones.
Effectiveness can depend on getting hormone dosing right through testing.
Convenience
HRT is easily and widely available as standard pills or patches.
Bioidentical hormones need custom compounding at special pharmacies.
Cost
HRT: Lower cost, covered by most insurers
Bioidenticals: Higher out of pocket costs. Limited insurance coverage.
Personalization
HRT offers fixed standard doses and combinations.
Bioidentical hormones allow custom compounding of exact hormones needed based on symptoms and deficiencies. Provides more flexibility in dosing.
In summary, while HRT offers standardized treatments with a known risk/benefit ratio,
bioidentical hormone therapy aims to provide personalized hormone solutions using identical molecules. Work with your health provider to determine what option might suit you best.
At Vitality Hormone Clinic, we specialize in bioidentical hormone replacement tailored to your unique needs. Our compounding pharmacy and lab uses cutting edge testing to guide precise and safe hormone therapy for symptoms of menopause, andropause and adrenal issues. Contact us today for a consultation.
